A specialized pro-resolving mediator; found in infected mouse spleens and resolving exudate

PCTR3 – 25 µg

Brand:
Cayman
CAS:
1810710-69-0
Storage:
-80
UN-No:
Non-Hazardous - 1170 / 3

Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; Item No. 90310).{38180,38178} DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 (Item No. 19064) by glutathione S-transferase and to PCTR2 (Item No. 19065) and PCTR3 via peptidases.{38180} PCTR3 is found in infected mouse spleens and resolving exudate as well as isolated human spleen and septic plasma.{38778} It is also found in both M1 and M2 macrophages differentiated from isolated human monocytes.{38179}  

 

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Description

A specialized pro-resolving mediator; found in infected mouse spleens and resolving exudate, isolated human spleen and septic plasma, and both M1 and M2 human macrophages

Formal name: 16R-[[(2R)-2-amino-2-carboxyethyl]thio]-17S-hydroxy-4Z,7Z,10Z,12E,14E,19Z-docosahexaenoic acid

Synonyms:  Protein Conjugates in Tissue Regeneration 3

Molecular weight: 463.6

CAS: 1810710-69-0

Purity: ≥96%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Docosanoids||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Specialized Pro-Resolving Mediators||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Infectious Disease||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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