A specialized pro-resolving mediator; found in resolving mouse exudate and both M1 and M2 human macrophages

PCTR2 – 25 µg

Brand:
Cayman
CAS:
1810710-63-4
Storage:
-80
UN-No:
Non-Hazardous - 1170 / 3

Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; Item No. 90310).{38180,38178} DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 (Item No. 19064) by glutathione S-transferase and to PCTR2 via γ-glutamyl transpeptidase.{38180} PCTR2 is found in resolving mouse exudate and in both M1 and M2 macrophages differentiated from isolated human monocytes.{38778,38179}  

 

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Description

A specialized pro-resolving mediator; found in resolving mouse exudate and both M1 and M2 human macrophages

Formal name: S-[(1R,2E,4E,6Z,9Z,12Z)-15-carboxy-1-[(1S,3Z)-1-hydroxy-3-hexen-1-yl]-2,4,6,9,12-pentadecapentaen-1-yl]-L-cysteinyl-glycine

Synonyms:  Protein Conjugates in Tissue Regeneration 2

Molecular weight: 520.7

CAS: 1810710-63-4

Purity: ≥96%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Docosanoids||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Specialized Pro-Resolving Mediators||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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