An alkaloid of the herbal drug M. speciosa; has opioid-like and stimulant effects; blocks the IKr

Paynantheine – 5 mg

Brand:
Cayman
CAS:
4697-66-9
Storage:
-20
UN-No:
Non-Hazardous - /

Paynantheine (Item No. 21841) is an alkaloid of the herbal drug M. speciosa (also known as kratom). Kratom (mitragynine; Item Nos. 11151 | 18567) has opioid-like and stimulant effects, and paynantheine can be detected in urine after kratom ingestion.{20201} Paynantheine blocks the delayed-rectifier potassium current in human induced pluripotent stem cell-derived cardiomyocytes (IC50 = 2.47 µM), suggesting that it may have cardiotoxic effects.{33930} This product is intended for research and forensic applications.  

 

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Description

An alkaloid of the herbal drug M. speciosa; has opioid-like and stimulant effects; blocks the IKr, in human induced pluripotent stem cell-derived cardiomyocytes (IC50 = 2.47 µM)

Formal name: (αE,2S,3R,12bS)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic acid, methyl ester

Synonyms:  (+)-Paynantheine

Molecular weight: 396.5

CAS: 4697-66-9

Purity: ≥98%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Opioids||Research Area|Forensic Chemistry & Toxicology|Stimulants

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