![A phenolic glycoside; prevents Aβ42-induced inhibition of NMDAR currents in rat hippocampal neurons at 2 μM; prevents Aβ42-induced inhibition of LTP in rats at 20 mg/kg; a 5-HT1A receptor agonist (Ki = 1.54 nM; EC50 = 34 nM for [35S]GTPγS binding); reverses phencyclidine-induced increases in immobility time in the forced swim test](https://interpriseusa.com/wp-content/uploads/2021/06/25127.png)
Description
A phenolic glycoside; prevents Aβ42-induced inhibition of NMDAR currents in rat hippocampal neurons at 2 μM; prevents Aβ42-induced inhibition of LTP in rats at 20 mg/kg; a 5-HT1A receptor agonist (Ki = 1.54 nM; EC50 = 34 nM for [35S]GTPγS binding); reverses phencyclidine-induced increases in immobility time in the forced swim test, phencyclidine-induced decreases in interaction time in the social interaction test, and reverses phencyclidine-induced impairments in visual recognition of a novel object in mice
Formal name: 3-carboxy-3-hydroxy-1,5-dioxo-1,5-pentanediylbis(oxymethylene-4,1-phenylene) bis-β-D-glucopyranoside
Synonyms:
Molecular weight: 728.7
CAS: 174972-80-6
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience
