Description
PTK is an analog of palmitic acid in which the COOH group is replaced by trifluoromethyl ketone. In P388D1 cells, PTK inhibits iPLA2 activity with an IC50 value of 3.8 µM.{1291} A related compound, ATK is a less potent inhibitor of iPLA2 with an IC50 value of 15 µM.{1291} PTK also inhibits the activity of cPLA2 with an IC50 value almost identical to that of ATK.{2992}
Formal name: 1,1,1-trifluoro-2-heptadecanone
Synonyms: Pentadeca Trifluoromethyl Ketone|PTK
Molecular weight: 308.4
CAS: 141022-99-3
Purity: ≥98%
Formulation: A solution in ethanol