A chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone

Palmitoyl thio-PC – 1 mg

Brand:
Cayman
CAS:
113881-60-0
Storage:
-20
UN-No:
Non-Hazardous - /

Thioester analogs of glycerophospholipids, in combination with Ellman’s reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity.{1358,1359} Palmitoyl thio-PC is a chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone. Hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB (Ellman’s reagent) giving a bright yellow product with an absorbance maximum at 412 nm. Palmitoyl thio-PC has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system.{15581}  

 

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SKU: 10010521 - 1 mg Category:

Description

A chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone

Formal name: 1-O-hexadecanoyl-2-thio-R-(hexadecanoyl)-sn-glycerol-3-phosphocholine

Synonyms: 

Molecular weight: 750.1

CAS: 113881-60-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases

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