PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and 'de novo' pathways.{939} It is less potent than PAF C-16 in the induction of platelet aggregation

PAF C-18 – 1 mg

Brand:
Cayman
CAS:
74389-69-8
Storage:
-20
UN-No:
- 1170 / 3

PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and ‘de novo’ pathways.{939} It is less potent than PAF C-16 in the induction of platelet aggregation, but equipotent in activation of guinea pig macrophages.{3786} PAF C-18 induces the release of PGE2 and TXB2 from albumin-elicited guinea pig macrophages, and enhances the spreading of plated macrophages.{640} Pathological processes involving PAF include necrotizing enterocolitis,{5841} inflammation, asthma, and allergy.{303}  

 

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SKU: 60910 - 1 mg Category:

Description

PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and ‘de novo’ pathways.{939} It is less potent than PAF C-16 in the induction of platelet aggregation, but equipotent in activation of guinea pig macrophages.{3786} PAF C-18 induces the release of PGE2 and TXB2 from albumin-elicited guinea pig macrophages, and enhances the spreading of plated macrophages.{640} Pathological processes involving PAF include necrotizing enterocolitis,{5841} inflammation, asthma, and allergy.{303}

Formal name: 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine

Synonyms: 

Molecular weight: 551.7

CAS: 74389-69-8

Purity: ≥97%

Formulation: A solution in ethanol

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