Description
An ATP-competitive inhibitor of p38 MAPKs; inhibits p38α, p38β, p38 , and p38δ MAPKs (IC50s = 0.13, 0.55, 5.47, and 8.63 μM, respectively); inhibits LPS-induced TNF-α and IL-1β cytokine production in human peripheral blood mononuclear cells (IC50s = 22 and 44 nM, respectively)
Formal name: 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)sulfonyl]-phenol
Synonyms: p38 MAP Kinase Inhibitor IV|p38 Mitogen-activated Protein Kinase Inhibitor IV
Molecular weight: 456.9
CAS: 1638-41-1
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|p38 MAPK||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|p38 MAPK Signaling||Research Area|Immunology & Inflammation|Innate Immunity
