A selective

Ozanimod – 1 mg

Brand:
Cayman
CAS:
1306760-87-1
Storage:
-20
UN-No:
Non-Hazardous - /

Ozanimod is a selective, orally available modulator of the sphingosine-1-phosphate (S1P) receptors S1P1 and SIP5.{32048,32049} It induces internalization of S1P1, decreases circulating B and CCR7(+) T lymphocytes, and reduces inflammation and disease parameters in three autoimmune disease models.{32048} Ozanimod is in clinical trials for relapsing multiple sclerosis and ulcerative colitis.{32048,32047}  

 

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SKU: 19922 - Category:

Description

A selective, orally available modulator of S1P1 and SIP5; induces internalization of S1P1, decreases circulating B and CCR7(+) T lymphocytes, and reduces inflammation and disease parameters in three autoimmune disease models

Formal name: 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)-benzonitrile

Synonyms: 

Molecular weight: 404.5

CAS: 1306760-87-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Allosteric Modulators||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Immunology & Inflammation|Gastric Disease|Ulcerative Colitis||Research Area|Lipid Biochemistry|Sphingolipids

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