Description
A selective inhibitor of TXA synthase (IC50 = 11 nM)
Formal name: 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2E-propenoic acid
Synonyms: OKY-046
Molecular weight: 228.3
CAS: 82571-53-7
Purity: ≥98%
Formulation: A crystalline solid
Ozagrel – 5 mg
Brand:
Cayman
CAS:
82571-53-7
Storage:
-20
UN-No:
Non-Hazardous - /
Inhibition of thromboxane synthase (TXAS), especially in human platelets, has been a clinical objective for many years. 1-Alkyl (N-alkyl)-imidazole derivatives have been recognized as TXAS inhibitors since the early 1980s.{10335,10334,10336} Ozagrel is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXAS with an IC50 of 11 nM. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke,{10146} and antihypertensive effects in spontaneously hypertensive rats.{10337}
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