A natural alkaloid with antiviral properties

Oxymatrine – 50 mg

Brand:
Cayman
CAS:
16837-52-8
Storage:
-20
UN-No:
Non-Hazardous - /

Oxymatrine is a natural alkaloid isolated from the root of S. flavescens, an herb used in traditional Chinese herbal medicine.{23832} It has antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine.{23830,23834} Oxymatrine also prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling.{23835,23833} This compound also induces apoptosis in certain cancer cells and ameliorates inflammation by impairing the translocation of nuclear factors-κB.{23832,23831}  

 

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Description

A natural alkaloid with antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine; prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling

Formal name: (4R,7aS,13aR,13bR,13cS)-dodecahydro-4-oxide-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one

Synonyms:  Matrine 1-oxide

Molecular weight: 264.4

CAS: 16837-52-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Alkaloids||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Hepatitis

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