A microbial metabolite with diverse biological activities; cytotoxic to A549

Oxychlororaphine – 5 mg

Brand:
Cayman
CAS:
550-89-0
Storage:
-20
UN-No:
Non-Hazardous - /

Oxychlororaphine is a phenazine microbial metabolite that has been found in a variety of bacteria and has anticancer, antibacterial, and antifungal activities.{48473,48474} It is cytotoxic to A549, HeLa, and SW480 cancer cells (IC50s = 32-40 μM).{48473} Oxychlororaphine halts the cell cycle at the G1 phase and induces apoptosis in A549 cells. It is active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi when used at concentrations ranging from 12.5 to 50 ppm.{48474}  

 

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SKU: 27624 - 5 mg Category:

Description

A microbial metabolite with diverse biological activities; cytotoxic to A549, HeLa, and SW480 cancer cells (IC50s = 32-40 μM); halts the cell cycle at the G1 phase and induces apoptosis in A549 cells; active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi from 12.5 to 50 ppm

Formal name: 1-phenazinecarboxamide

Synonyms: 

Molecular weight: 223.2

CAS: 550-89-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases|Candidiasis||Research Area|Infectious Disease|Fungal Diseases|Ringworm

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