Description
An inhibitor of xanthine oxidase and active metabolite of allopurinol; formed by oxidation of allopurinol; binds to an enzyme-bound molybdenum cofactor that keeps xanthine oxidase in an inactive state; inhibits de novo purine and pyrimidine biosynthesis in human fibroblast cultures; inhibits the growth of L. donovani from 20-50 µg/ml
Formal name: 1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
Synonyms: Alloxanthine|NSC 76239
Molecular weight: 152.1
CAS: 2465-59-0
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Infectious Disease|Parasitic Diseases|Leishmaniasis||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Xanthine Oxidase||Research Area|Toxicology|Drug Metabolism|Drug Metabolites