Description
The oxidation of low density lipoprotein is thought to be one of the first steps in atherosclerosis. The uptake of oxidized LDL (oxLDL) by macrophages activates pro-inflammatory mediators that promote disease progression. Cayman’s Oxidized LDL Uptake Assay Kit is a convenient tool to study modulators of cellular uptake of oxLDL. The kit employs a fluorescently tagged, human oxLDL along with myricetin, an inhibitor of uptake that reduces CD36 expression. The reagents provided in this kit are sufficient to run a single plate of cultured cells by either FC or FM.
Formulation:
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Synonyms: oxLDL
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Imunogen:
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Application|Cell-Based Assay||Application|Flow Cytometry||Application|Fluorescence||Application|Multiplex||Product Type|Assay Kits|Cell-Based Assays||Product Type|Assay Kits|Inhibitor Screening Assays||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins
