A benzimidazole anthelmintic; inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin and inhibits mammalian tubulin polymerization (IC50s = 0.3 and 2.2 µM

Oxibendazole – 250 mg

Brand:
Cayman
CAS:
20559-55-1
Storage:
-20
UN-No:
Non-Hazardous - /

Oxibendazole is a benzimidazole anthelmintic.{41688} It inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin and inhibits mammalian tubulin polymerization (IC50s = 0.3 and 2.2 µM, respectively).{41688} When used in combination with the anthelmintic niclosamide (Item No. 10649), oxibendazole (15 mg/kg) reduces fecal worm egg counts in dogs and cats by greater than 90% for the nematodes T. canis, T. vulpis, A. caninum, and T. leonine.{45308} It also reduces fecal egg counts of strongyles in horses when administered at a dose of 10 mg/kg per day.{45309} Formulations containing oxibendazole have been used in the prevention and treatment of parasitic worm infections in dogs and the treatment of parasitic worm infections in horses.  

 

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SKU: 27365 - 250 mg Category:

Description

A benzimidazole anthelmintic; inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin and inhibits mammalian tubulin polymerization (IC50s = 0.3 and 2.2 µM, respectively); reduces fecal worm egg counts in dogs and cats by greater than 90% for the nematodes T. canis, T. vulpis, A. caninum, and T. leonine at 15 mg/kg in combination with niclosamide; reduces fecal egg counts of strongyles in horses at 10 mg/kg per day

Formal name: N-(6-propoxy-1H-benzimidazol-2-yl)-carbamic acid, methyl ester

Synonyms: 

Molecular weight: 249.3

CAS: 20559-55-1

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Anthelmintics||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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