A potent inhibitor of HDACs (IC50 = 15.7 nM); has been shown to alter the expression of several genes whose products are involved in cell morphology

Oxamflatin – 5 mg

Brand:
Cayman
CAS:
151720-43-3
Storage:
-20
UN-No:
Non-Hazardous - /

Oxamflatin is a potent inhibitor of histone deacetylases (IC50 = 15.7 nM).{18443} It has been shown to alter the expression of several genes whose products are involved in cell morphology, motility, apoptosis, and cell cycle control, reducing the proliferation of cancer cells.{18441,18442,18443}  

 

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Description

A potent inhibitor of HDACs (IC50 = 15.7 nM); has been shown to alter the expression of several genes whose products are involved in cell morphology, motility, apoptosis, and cell cycle control, reducing the proliferation of cancer cells

Formal name: N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-2E-penten-4-ynamide

Synonyms:  Metacept 3

Molecular weight: 342.4

CAS: 151720-43-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Deacetylases||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation

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