A 33 amino acid hypothalamic neuropeptide with a role in appetite regulation

Orexin A (bovine, human, mouse, rat) – 1 mg

Brand:
Cayman
CAS:
205640-90-0
Storage:
-20
UN-No:
Non-Hazardous - /

Orexin A is a 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, hypothalamic-pituitary-adrenal activity, and pain thresholds.{17942} Orexin signaling is activated by nutrient depletion, causing an increase in food intake by delaying the signals of satiety.{6718} It activates the orexin-1 and -2 receptors with equal affinity (EC50s = 0.09 and 0.06 μM, respectively).{24277}  

 

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Description

A 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, sympathetic and HPA activity, and pain thresholds; binds the orexin-1 and -2 receptors with equal affinity

Formal name:

Synonyms:  Hypocretin 1|OXA

Molecular weight: 3,561.10

CAS: 205640-90-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Peptides|Neuropeptides||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Neuroscience|Behavioral Neuroscience|Food Intake||Research Area|Neuroscience|Neuroendocrinology||Research Area|Neuroscience|Pain Research

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