An intermediate used in the production of the gastric proton pump inhibitors

Omeprazole sulfide – 250 mg

Brand:
Cayman
CAS:
73590-85-9
Storage:
-20
UN-No:
Non-Hazardous - /

Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole (Item No. 14880) and esomeprazole (Item No. 17326).{31117} As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 µM).{30672}  

 

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Description

An intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole; upon degradation it can inhibit CYP2C19 in pooled human liver microsomes (IC50 = 9.7 µM)

Formal name: 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole

Synonyms:  Pyrmetazole|Ufiprazole

Molecular weight: 329.4

CAS: 73590-85-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Synthetic Intermediates & Building Blocks||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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