A minor component of the oligomycin complex that acts as an inhibitor of the mitochondrial F1FO-ATP synthase

Oligomycin C – 1 mg

Brand:
Cayman
CAS:
11052-72-5
Storage:
-20
UN-No:
Non-Hazardous - /

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin C is a minor component of the oligomycin complex (Item No. 11341) that acts as an inhibitor of the mitochondrial F1FO-ATP synthase.{27897} Inhibition of the ATP synthase by oligomycins leads to cell death.{30742}  

 

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Description

A minor component of the oligomycin complex that acts as an inhibitor of the mitochondrial F1FO-ATP synthase, which leads to cell death

Formal name: (1R,​2’R,​4E,​5’S,​6S,​6’S,​7R,​8S,​10R,​11S,​12S,​14S,​15S,​16R,​18E,​20E,​22R,​25S,​28S,​29R)​-22-​ethyl-​3′,​4′,​5′,​6′-​tetrahydro-​7,​11,​15-​trihydroxy-​6′-​[(2R)​-​2-​hydroxypropyl]​-​5′,​6,​8,​10,​12,​14,​16,​28,​29-​nonamethyl-spiro[2,​26-​dioxabicyclo[23.3.1]​nonacosa-​4,​18,​20-​triene-​27,​2′-​[2H]​pyran]​-​3,​9,​13-​trione

Synonyms:  12-deoxy Oligomycin A

Molecular weight: 775.1

CAS: 11052-72-5

Purity: ≥95%

Formulation: A white lyophilisate

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cell Biology|Mitochondrial Biology

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