A selective FAAH inhibitor (IC50 = 5.25 nM in rat brain homogenates) with potential analgesic and anxiolytic activity; does not inhibit acidic PEAase or bind to CB1 or CB2 receptors

Oleoyl Ethyl Amide – 5 mg

Brand:
Cayman
CAS:
85075-82-7
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Numerous analogs of fatty acyl ethanolamides potentiate the intrinsic biological activity of arachidonoyl ethanolamide (anandamide; AEA).{10254} This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty amide acyl hydrolase (FAAH) within the neurons.{10647} Oleoyl ethyl amide (OEtA) has potent FAAH inhibitory activity (IC50 5.25 nM in rat brain homogenates) but does not inhibit acidic PEAase or bind to CB1 or CB2 receptors. OEtA is therefore a selective FAAH inhibitor with potential analgesic and anxiolytic activity.{11985}  

 

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SKU: 10005459 - 5 mg Category:

Description

A selective FAAH inhibitor (IC50 = 5.25 nM in rat brain homogenates) with potential analgesic and anxiolytic activity; does not inhibit acidic PEAase or bind to CB1 or CB2 receptors

Formal name: N-ethyl-9Z-octadecenamide

Synonyms:  N-Ethyloleamide|OEtA

Molecular weight: 309.5

CAS: 85075-82-7

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Fatty Amides||Product Type|Biochemicals|Lipids|Octadecanoids||Product Type|Biochemicals|Small Molecule Inhibitors|Fatty Acid Metabolism||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids||Research Area|Neuroscience|Pain Research

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