An internal standard for the quantification of OEA by GC- or LC-MS.

Oleoyl Ethanolamide-d2 – 500 µg

Brand:
Cayman
CAS:
1245477-09-1
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Oleoyl ethanolamide-d2 (OEA-d2) contains two deuterium atoms at the 11 position. It is intended for use as an internal standard for the quantification of OEA by GC- or LC-mass spectrometry. OEA is an analogue of the endocannabinoid arachidonoyl ethanolamide (AEA) found in brain tissue and in chocolate.{5291} It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue,{2874} but its biosynthesis is reduced in the intestine of rats following food deprivation.{9302} OEA is an endogenous, potent agonist for peroxisome proliferator-activated receptor α (PPARα), exhibiting an EC50 value of 120 nM in a transactivation assay.{11423} Systemic administration of OEA suppresses food intake and reduces weight gain in rats (10 mg/kg intraperitoneally) and PPARα wild-type mice, but not in PPARα knockout mice.{9302,11423} These data indicate that OEA regulates food intake by a PPARα-mediated mechanism.  

 

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SKU: 10007823 - 500 µg Category:

Description

An internal standard for the quantification of OEA by GC- or LC-MS.

Formal name: N-(2-hydroxyethyl)-9Z-octadecenamide-11,11-d2

Synonyms:  OEA-d2|Oleic Acid Ethanolamide-d2

Molecular weight: 327.5

CAS: 1245477-09-1

Purity: ≥99% deuterated forms (d1-d2)

Formulation: A solution in ethanol

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Fatty Amides||Product Type|Biochemicals|Lipids|Octadecanoids||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Endocrinology & Metabolism|Hormones & Receptors|PPARs||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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