ACAT is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.{13122} Oleic acid-2

Oleic Acid-2,6-diisopropylanilide – 5 mg

Brand:
Cayman
CAS:
140112-65-8
Storage:
-20
UN-No:
De Minimis - 1231 / 3

AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.{13122} Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.{12463} When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%.  

 

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SKU: 10006782 - 5 mg Category:

Description

ACAT is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.{13122} Oleic acid-2,6-diisopropylanilide is an inhibitor of ACAT with an IC50 of 7 nM.{12463} When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased LDL and elevated HDL levels when administered at 0.05%.

Formal name: N-[2,6-bis(1-methylethyl)phenyl]-9Z-octadecenamide

Synonyms: 

Molecular weight: 441.7

CAS: 140112-65-8

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias

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