An internal standard for the quantification of oleic acid by GC- or LC-MS

Oleic Acid-13C – 10 mg

Brand:
Cayman
CAS:
82005-44-5
Storage:
-20
UN-No:
Excepted Quantity - 1170 / 3

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid (Item Nos. 90260 | 24659) by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.{3964,42296} It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.{3964} Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 µg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 µM, similar to arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).{2095} Oleic acid (60 µM) induces release of intracellular calcium in human platelets.{4198} In vivo, oleic acid increases TNF-α, IL-8, IL-6, and IL-1β production, neutrophil accumulation, and apoptotic and necrotic cell death in mouse lung and has been used to induce lung injury in a mouse model of acute respiratory distress syndrome (ARDS).{42296}  

 

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SKU: 27869 - 10 mg Category:

Description

An internal standard for the quantification of oleic acid by GC- or LC-MS

Formal name: 9Z-octadecenoic-1-13C acid

Synonyms:  9Z-Octadecenoic Acid-13C|9Z-Oleic Acid-13C|C18:1-13C

Molecular weight: 283.5

CAS: 82005-44-5

Purity: ≥98%

Formulation: A solution in ethanol

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|13C||Product Type|Biochemicals|Lipids|Fatty Acids||Product Type|Biochemicals|Lipids|Octadecanoids||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Death|Necrosis||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases||Research Area|Lipid Biochemistry|Fatty Acids

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