A triterpene with diverse biological activities; active against P. gingivalis (MIC = 39 µg/ml); induces apoptosis in and reduces viability of HCT116 colon carcinoma cells from 5-50 µM; induces apoptosis of HUVECs in vitro and inhibits capillary vessel formation in a Matrigel™ plug assay in mice; reduces the number of skin lesions

Oleanolic Acid Acetate – 1 mg

Brand:
Cayman
CAS:
4339-72-4
Storage:
-20
UN-No:
Non-Hazardous - /

Oleanolic acid acetate is a triterpene that has been found in the root bark of M. macrophylla and has diverse biological activities.{48970,48971,48972,48973} It is active against P. gingivalis (MIC = 39 µg/ml).{48970} Oleanolic acid acetate (5-50 µM) induces apoptosis in and reduces viability of HCT116 colon carcinoma cells.{48971} It induces apoptosis in human umbilical vein endothelial cells (HUVECs) in vitro and inhibits capillary vessel formation in a Matrigel™ plug assay in mice.{48972} Oleanolic acid acetate (2, 10, and 50 mg/kg) reduces the number of skin lesions, epidermal thickness and immune cell infiltration, and serum IgE, IgG2a, and histamine levels in a mouse model of atopic dermatitis.{48973}  

 

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SKU: 29764 - 1 mg Category:

Description

A triterpene with diverse biological activities; active against P. gingivalis (MIC = 39 µg/ml); induces apoptosis in and reduces viability of HCT116 colon carcinoma cells from 5-50 µM; induces apoptosis of HUVECs in vitro and inhibits capillary vessel formation in a Matrigel™ plug assay in mice; reduces the number of skin lesions, epidermal thickness and immune cell infiltration, and serum IgE, IgG2a, and histamine levels in a mouse model of atopic dermatitis at 2, 10, and 50 mg/kg

Formal name: 3β-(acetyloxy)-olean-12-en-28-oic acid

Synonyms:  3-Acetyloleanolic Acid

Molecular weight: 498.7

CAS: 4339-72-4

Purity: ≥95%

Formulation: A solid

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