A mycotoxin; increases lipid peroxide levels and the number of apoptotic cells

Ochratoxin A – 5 mg

Brand:
Cayman
CAS:
303-47-9
Storage:
-20
UN-No:
De Minimis - 3462 / 6.1

Ochratoxin A (OTA) is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.{57301} Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.{21686}  

 

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SKU: 11439 - 5 mg Category:

Description

A mycotoxin; increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney at 120 μg/kg; topical application induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells at 80 μg/mouse; initiates tumor formation in a two-stage mouse skin tumorigenesis model; has been found as a contaminant in a variety of foods

Formal name: N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine

Synonyms:  NSC 201422|NSC 221991|OTA

Molecular weight: 403.8

CAS: 303-47-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents||Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Cancer||Research Area|Cell Biology|Cell Cycle||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Pro-oxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase||Research Area|Toxicology|Cell Health & Viability

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