Description
A peptide hormone; binds to the orphan receptor GPR39 (Kd = 1 nM) and stimulates cAMP production in CHO and HEK293 cells overexpressing human GPR39; suppresses food intake in a time- and dose-dependent manner and reduces body weight gain and gastric emptying in mice (12.5-1,000 nmol/kg); reduces food intake and glucose response without affecting plasma insulin responses in fasted high-fat diet fed mice (0.22 g per animal) ,
Formal name: L-phenylalanyl-L-asparaginyl-L-alanyl-L-prolyl-L-phenylalanyl-L-α-aspartyl-L-valylglycyl-L-isoleucyl-L-lysyl-L-leucyl-L-serylglycyl-L-valyl-L-glutaminyl-L-tyrosyl-L-glutaminyl-L-glutaminyl-L-histidyl-L-seryl-L-glutaminyl-L-alanyl-L-leucinamide
Synonyms:
Molecular weight: 2,546.80
CAS: 1081110-72-6
Purity: ≥95%
Formulation: A lyophilized powder
Product Type|Biochemicals|Peptides|Peptide Hormones||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity
