A potent inducer of Oct3/4 expression and translation in human cell lines and in terminally differentiated human fibroblasts; promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts

O4I2 – 10 mg

Brand:
Cayman
CAS:
165682-93-9
Storage:
-20
UN-No:
Non-Hazardous - /

Octamer-binding transcription factor 3/4 (Oct3/4) is a transcription factor that has key roles in early embryogenesis and embryonic stem cell pluripotency.{22412,22414} O4I2 is a potent inducer of Oct3/4 expression and translation in human cell lines, including embryonic kidney HEK293, embryonic placental NCCIT, and Oct-deficient HeLa cells.{30986} It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I2 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.{30986}  

 

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Description

A potent inducer of Oct3/4 expression and translation in human cell lines and in terminally differentiated human fibroblasts; promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts

Formal name: 2-[(4-chlorophenyl)amino]- 4-thiazolecarboxylic acid, ethyl ester

Synonyms: 

Molecular weight: 282.7

CAS: 165682-93-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Transcription Factors & Coactivators||Research Area|Cell Biology|Stem Cell Research||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors

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