An agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM); mimics the phosphatidylserine head group and has been shown to inhibit the proliferation of microglia and to enhance neuronal differentiation of progenitor cells

O-Phospho-L-Serine – 5 g

Brand:
Cayman
CAS:
407-41-0
Storage:
-20
UN-No:
Non-Hazardous - /

O-Phospho-L-Serine is an agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM).{26379,26380} It mimics the phosphatidylserine head group and has been shown to inhibit the proliferation of microglia and to enhance neuronal differentiation of progenitor cells.{26378,26381,26377}  

 

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Description

An agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM); mimics the phosphatidylserine head group and has been shown to inhibit the proliferation of microglia and to enhance neuronal differentiation of progenitor cells

Formal name: O-phosphono-L-serine

Synonyms:  Dexfosfoserine|L-Serine-O-Phosphate|L-SOP

Molecular weight: 185.1

CAS: 407-41-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience

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