A natural alkaloid mycotoxin that blocks activation of the HIV LTR by TNF-α in HeLa cells (IC50 = 5 µM); inhibits virus production in OM-10.1 cells (HL-60 promyelocytes infected with HIV-1) treated with TNF-α (IC50 = 2.5 µM)

O-Methylviridicatin – 1 mg

Brand:
Cayman
CAS:
6152-57-4
Storage:
-20
UN-No:
Non-Hazardous - /

O-Methylviridicatin is a natural derivative of the alkaloid mycotoxin viridicatin, which is produced by several species of Penicillium.{31092} O-Methylviridicatin blocks activation of the HIV long terminal repeat by TNF-α in HeLa cells (IC50 = 5 µM).{31091} It also inhibits virus production in OM-10.1 cells (HL-60 promyelocytes infected with HIV-1) treated with TNF-α (IC50 = 2.5 µM).{31091}  

 

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Description

A natural alkaloid mycotoxin that blocks activation of the HIV LTR by TNF-α in HeLa cells (IC50 = 5 µM); inhibits virus production in OM-10.1 cells (HL-60 promyelocytes infected with HIV-1) treated with TNF-α (IC50 = 2.5 µM)

Formal name: 3-methoxy-4-phenyl-2(1H)-quinolinone

Synonyms:  3-methoxy-4-phenyl-Carbostyril|AIDS-089094|Viridicatin methyl ester

Molecular weight: 251.3

CAS: 6152-57-4

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS

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