A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM

O-2545 (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
874745-43-4
Storage:
-20
UN-No:
Non-Hazardous - /

Cannabinoid agonists are typically highly lipophilic compounds that require solubilization with either a surfactant agent or adherence to a water miscible substance such as albumin, Tween 80, or Emulphor. O-2545 is a potent water-soluble agonist of central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 1.5 and 0.32 nM, respectively.{14718} When dissolved in saline, O-2545 was highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly.{14718}  

 

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SKU: 10009195 - 10 mg Category:

Description

A potent water-soluble agonist of CB1 and CB2 receptors with Ki values of 1.5 and 0.32 nM, respectively; when dissolved in saline, is highly efficacious in mouse behavioral models when administered either intravenously or intracerebroventricularly

Formal name: 6a,7,10,10a-tetrahydro-3-[5-(1H-imidazol-1-yl)-1,1-dimethylpentyl]-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol, monohydrochloride

Synonyms: 

Molecular weight: 445

CAS: 874745-43-4

Purity: ≥98%

Formulation: A lyophilized powder

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors

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