Description
An antiviral; prevents influenza nucleoprotein from accumulating in the nucleus; inhibits MDCK cell infection by influenza A and H5N1 (EC50s = 0.069 and 0.33 µM, respectively), as well as a clinical isolate of H3N2 (EC50 = 0.16 µM); reduces the lung viral load and increases the survival rate in a mouse model of influenza H5N1 infection
Formal name: [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)-methanone
Synonyms:
Molecular weight: 426.9
CAS: 341001-38-5
Purity: ≥98%
Formulation: A crystalline solid
