A small molecule inhibitor of RPA70 dsDNA binding; selectively inhibits dsDNA over ssDNA binding to RPA70 from 25-400 µM; inhibits the protein-protein interaction between p53 or Rad9 and RPA70

NSC 15520 – 25 mg

Brand:
Cayman
CAS:
730960-98-2
Storage:
-20
UN-No:
Non-Hazardous - /

NSC 15520 is an inhibitor of replication protein A 70 (RPA70) dsDNA binding.{44008} It selectively inhibits dsDNA over ssDNA binding to RPA70 when used at concentrations ranging from 25 to 400 µM. NSC 15520 also inhibits the protein-protein interaction between the cell cycle checkpoint control proteins p53 or Rad9 and RPA70.  

 

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SKU: 26020 - 25 mg Category:

Description

A small molecule inhibitor of RPA70 dsDNA binding; selectively inhibits dsDNA over ssDNA binding to RPA70 from 25-400 µM; inhibits the protein-protein interaction between p53 or Rad9 and RPA70

Formal name: 4,4a,4b,5,6,7,8,8a,9,10-decahydro-4b,8-dimethyl-2-(1-methylethyl)-3H-3,10a-ethanophenanthrene-8,11,12-tricarboxylic acid

Synonyms: 

Molecular weight: 418.5

CAS: 730960-98-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cell Biology|Cell Cycle

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