a thiopeptide antibiotic effective against many different methicillin-resistant S. aureus strains (MICs ≤ 0.25 mg/L)

Nosiheptide – 5 mg

Brand:
Cayman
CAS:
56377-79-8
Storage:
-20
UN-No:
Non-Hazardous - /

Nosiheptide is a thiopeptide antibiotic that inhibits bacterial protein synthesis by interfering with the function of elongation factors.{27776,27778} It is effective against many different methicillin-resistant S. aureus strains (MICs ≤ 0.25 mg/L), Enterococcus spp (MICs ≤ 0.125 mg/L), and the BI strain of C. difficile (MIC = 0.008 mg/L) but inactive against most Gram-negative bacteria.{27777}  

 

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Description

a thiopeptide antibiotic effective against many different methicillin-resistant S. aureus strains (MICs ≤ 0.25 mg/L), Enterococcus spp (MICs ≤ 0.125 mg/L), and the BI strain of C. difficile (MIC = 0.008 mg/L) but inactive against most Gram-negative bacteria

Formal name: N-[1-(aminocarbonyl)ethenyl]-2-[(11S,14Z,21S,23S,29S)-14-ethylidene-9,10,11,12,13,14,19,20,21,22,23,24,26,33,35,36-hexadecahydro-3,23-dihydroxy-11-[(1R)-1-hydroxyethyl]-31-methyl-9,12,19,24,33,43-hexaoxo-30,32-imino-8,5:18,15:40,37-trinitrilo-21,36-([2,4]-endothiazolomethanimino)-4-thiazolecarboxamide

Synonyms:  Multhiomycin|NSC 307240|RP 9671

Molecular weight: 1,222.40

CAS: 56377-79-8

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Polypeptides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA

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