A lichen metabolite; active against A. hydrophilia

Norstictic Acid – 1 mg

Brand:
Cayman
CAS:
571-67-5
Storage:
-20
UN-No:
Non-Hazardous - /

Norstictic acid is a lichen metabolite that has been found in R. farinacea and has antimicrobial and anticancer activities.{48720,48721} It is active against A. hydrophilia, B. subtilis, L. monocytogenes, P. vulgaris, S. faecalis, C. albicans, and C. glabrata (MICs = 0.1-6.7 mM).{48720} Norstictic acid (1-100 μM) inhibits proliferation, migration, and invasion of MDA-MB-231 cells.{48721} In vivo, norstictic acid (15 mg/kg, i.p.) reduces tumor growth in an MDA-MB-231/GFP mouse xenograft model.  

 

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SKU: 29581 - 1 mg Category:

Description

A lichen metabolite; active against A. hydrophilia, B. subtilis, L. monocytogenes, P. vulgaris, S. faecalis, C. albicans, and C. glabrata (MICs = 0.1-6.7 mM); inhibits proliferation, migration, and invasion of MDA-MB-231 cells from 1-100 μM; reduces tumor growth in an MDA-MB-231/GFP mouse xenograft model at 100 mg/kg

Formal name: 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-7H-isobenzofuro[4,5-b][1,4]benzodioxepin-11-carboxaldehyde

Synonyms: 

Molecular weight: 372.3

CAS: 571-67-5

Purity: ≥95%

Formulation: A solid

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