A fluoroquinolone antibiotic; inhibits the growth of Gram-positive and Gram-negative bacteria (MICs = 4 and 1 μg/ml for S. aureus and P. aeruginosa

Norfloxacin – 10 g

Brand:
Cayman
CAS:
70458-96-7
Storage:
4
UN-No:
Non-Hazardous - /

Norfloxacin is a fluoroquinolone antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria (MICs = 4 and 1 μg/ml for S. aureus and P. aeruginosa, respectively).{45096} It also inhibits the growth S. pseudintermedius, S. aureus, E. coli, Pasturella, and S. canis isolates from dogs (mean MIC50s = 0.25, 1, 0.03, 1, and 1 μg/ml, respectively).{39898} Topical administration of norfloxacin (0.1% v/v) reduces corneal ulcer size in a rabbit model of P. aeruginosa corneal infection. It also prevents encrusted cystitis in bladder and increases survival in a rat model of Corynebacterium group D2 infection when administered at a dose of 80 mg/kg per day.{45097} Formulations containing norfloxacin have been used to treat urinary tract and gynecological infections.  

 

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SKU: 25975 - 10 g Category:

Description

A fluoroquinolone antibiotic; inhibits the growth of Gram-positive and Gram-negative bacteria (MICs = 4 and 1 μg/ml for S. aureus and P. aeruginosa, respectively); inhibits the growth S. pseudintermedius, S. aureus, E. coli, Pasturella, and S. canis isolates from dogs (mean MIC50s = 0.25, 1, 0.03, 1, and 1 μg/ml, respectively); topical administration reduces corneal ulcer size in a rabbit model of P. aeruginosa corneal infection at 0.1 % v/v; prevents encrusted cystitis in bladder and increases survival in a rat model of Corynebacterium group D2 infection at 80 mg/kg/day

Formal name: 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

Synonyms: 

Molecular weight: 319.3

CAS: 70458-96-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Quinolones & Fluoroquinolones||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Neuroscience|Ophthalmology

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