A cell-permeable

nNOS Inhibitor I – 1 mg

Brand:
Cayman
CAS:
357965-99-2
Storage:
-20
UN-No:
De Minimis - 1170 / 3

nNOS inhibitor I is a cell-permeable, selective inhibitor of nNOS (Ki = 120 nM).{32654} It displays >2,500-fold and 320-fold selectivity over eNOS and iNOS, respectively.{32654} It has been used in a rabbit model for cerebral palsy to prevent hypoxia-ischemia-induced death and to reduce the number of newborn kits exhibiting signs of cerebral palsy.{32655}  

 

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Description

A cell-permeable, selective inhibitor of nNOS (Ki = 120 nM)

Formal name: N-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-N’-nitro-guanidine, tris(2,2,2-trifluoroacetate)

Synonyms:  ncNOS|Neuronal Nitric Oxide Synthase|NOS I

Molecular weight: 589.4

CAS: 357965-99-2

Purity: ≥95%

Formulation: A solution in ethanol

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Nitric Oxide Synthases||Research Area|Neuroscience|Neuroprotection|Ischemia

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