A cell-permeable

NNGH – 5 mg

Brand:
Cayman
CAS:
161314-17-6
Storage:
22
UN-No:
Non-Hazardous - /

NNGH is a cell-permeable, broad-spectrum inhibitor of matrix metalloproteinases (MMPs). It blocks the activity of MMP-8, -9, -12, -13, and -20 with Ki values of 9, 2.6, 4.3, 3.1, and 17 nM, respectively.{27721,18673} It also inhibits MMP-1, -3, -7, and -10 with Ki values of 0.17, 0.13, 13, and 0.1 µM, respectively.{27721,18673} It is commonly used to study the role of MMP-3 (stromelysin 1) in biological systems.{27723,27724,27722}  

 

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Description

A cell-permeable, broad-spectrum inhibitor of MMPs; blocks the activity of MMP-8, -9, -12, -13, and -20 with Ki values of 9, 2.6, 4.3, 3.1, and 17 nM, respectively; also inhibits MMP-1, -3, -7, and -10 with Ki values of 0.17, 0.13, 13, and 0.1 µM, respectively

Formal name: N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino]-acetamide

Synonyms:  ​​Matrix Metalloproteinase-3 Inhibitor II|MMP-3 Inhibitor II|N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl Hydroxamic Acid

Molecular weight: 316.4

CAS: 161314-17-6

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area

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