An antibiotic; reduces E. coli replication and abscess formation in the renal medulla of infected rats in a dose-dependent manner when administered at doses ranging from 25-100 mg/kg; prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates of P. mirabilis; prevents alkalization of urine as well as calculi and abscess formation in a rat model of P. vulgaris urinary tract infection

Nitrofurantoin – 10 g

Brand:
Cayman
CAS:
67-20-9
Storage:
22
UN-No:
Non-Hazardous - /

Nitrofurantoin is an antibiotic.{41357} In vivo, nitrofurantoin (25-100 mg/kg, i.m.) reduces E. coli replication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates of P. mirabilis. Nitrofurantoin also prevents alkalization of urine as well as calculi and abscess formation in a rat model of P. vulgaris urinary tract infection.{41358} Formulations containing nitrofurantoin have been used to treat urinary tract infections.  

 

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SKU: 23510 - 10 g Category:

Description

An antibiotic; reduces E. coli replication and abscess formation in the renal medulla of infected rats in a dose-dependent manner when administered at doses ranging from 25-100 mg/kg; prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates of P. mirabilis; prevents alkalization of urine as well as calculi and abscess formation in a rat model of P. vulgaris urinary tract infection

Formal name: 1-[[(5-nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione

Synonyms:  NSC 2107|NSC 44150

Molecular weight: 238.2

CAS: 67-20-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Nitrofurans||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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