A chromogenic cephalosporin substrate commonly used to detect β-lactamases in bacteria and other microbes

Nitrocefin – 5 mg

Brand:
Cayman
CAS:
41906-86-9
Storage:
-20
UN-No:
Non-Hazardous - /

The generation of β-lactamases by bacteria affords resistance to several classes of β-lactam antibiotics, including penicillins and cephalosporins.{25960} Nitrocefin is a chromogenic cephalosporin substrate commonly used to detect β-lactamases in bacteria.{25959,25958,25957} The presence of β-lactamase activity is indicated by the appearance of a red color that is proportional in intensity to the original concentration of nitrocefin.{25959}  

 

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Description

A chromogenic cephalosporin substrate commonly used to detect β-lactamases in bacteria and other microbes

Formal name: (6R)-3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7R-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Synonyms:  Nitrocephin

Molecular weight: 516.5

CAS: 41906-86-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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