A limonoid with diverse biological activities; inhibits the growth of D. oryzae by 64.8% at 1

Nimbin – 1 mg

Brand:
Cayman
CAS:
5945-86-8
Storage:
-20
UN-No:
Non-Hazardous - /

Nimbin is a limonoid that has been found in neem seeds and has diverse biological activities.{52347,52348,46670} It inhibits the growth of the plant pathogenic fungus D. oryzae by 64.8% when used at a concentration of 1,000 ppm.{52347} Nimbin (0.02-2,000 μM) has antifeedant activity against S. littoralis in a choice test.{52348} It decreases melanin content to 20.9% of control, without affecting viability, in B16 murine melanoma cells when used at a concentration of 25 μg/ml.{46670} Nimbin inhibits activation of Epstein-Barr virus early antigen (EBV-EA) induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in Raji cells (IC50 = 499 mol ratio/32 pmol TPA).  

 

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SKU: 29884 - 1 mg Category:

Description

A limonoid with diverse biological activities; inhibits the growth of D. oryzae by 64.8% at 1,000 ppm; has antifeedant activity against S. littoralis in a choice test at 0.02-2,000 μM; decreases melanin content to 20.9% of control in B16 murine melanoma cells at 25 μg/ml; inhibits TPA-induced activation of EBV-EA in Raji cells (IC50 = 499 mol ratio/32 pmol TPA)

Formal name: (2R,3aR,4aS,5R,5aR,6R,9aR,10S,10aR)-5-(acetyloxy)-2-(3-furanyl)-3,3a,4a,5,5a,6,9,9a,10,10a-decahydro-6-(methoxycarbonyl)-1,6,9a,10a-tetramethyl-9-oxo-2H-cyclopenta[b]naphtho[2,3-d]furan-10-acetic acid, methyl ester

Synonyms: 

Molecular weight: 540.6

CAS: 5945-86-8

Purity: ≥98%

Formulation: A solid

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