A depsidone; active against the bacteria M. tuberculosis and M. ranoe

Nidulin – 5 mg

Brand:
Cayman
CAS:
10089-10-8
Storage:
-20
UN-No:
Non-Hazardous - /

Nidulin is a depsidone originally isolated from A. nidulans.{38475} It is active against the bacteria M. tuberculosis and M. ranoe, as well as the fungi T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 4 µg/ml) and has larvicidal activity toward Artemia (LC50 = 2.8 µg/ml).{38476} Nidulin is cytotoxic to MOLT-3 cells (IC50 = 21.2 µM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >112.7 µM). It inhibits aromatase with an IC50 value of 11.2 µM.{38477}  

 

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SKU: 27955 - 5 mg Category:

Description

A depsidone; active against the bacteria M. tuberculosis and M. ranoe, as well as the fungi T. tonsurans and M. audouini; inhibits the growth of MRSA (MIC = 4 µg/ml); has larvicidal activity toward Artemia (LC50 = 2.8 µg/ml); inhibits the E. coli strain AB3027(-) (MIC = 4 µg/ml); cytotoxic to MOLT-3 cells (IC50 = 21.2 µM); inhibits aromatase (IC50 = 11.2 µM)

Formal name: 2,4,7-trichloro-3-hydroxy-8-methoxy-1,9-dimethyl-6-[(1E)-1-methyl-1-propen-1-yl]-11H-dibenzo[b,e][1,4]dioxepin-11-one

Synonyms:  Methylustin

Molecular weight: 443.7

CAS: 10089-10-8

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Pesticides|Insecticides||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cancer|Cell Death

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