A fluorescent probe that crosses the blood-brain barrier; binds with high affinity to Aβ plaques (Ki = 10 nM); ex/em spectra = 475/625 nm

NIAD-4 – 10 mg

Brand:
Cayman
CAS:
868592-56-7
Storage:
-20
UN-No:
Non-Hazardous - /

NIAD-4 is a fluorescent probe that crosses the blood-brain barrier to bind with high affinity to amyloid-β (Aβ) plaques (Ki = 10 nM).{29747} It displays excitation/emission spectra of 475/625 nm, respectively, with the far-red emission occurring upon binding to Aβ.  

 

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Description

A fluorescent probe that crosses the blood-brain barrier; binds with high affinity to Aβ plaques (Ki = 10 nM); ex/em spectra = 475/625 nm, respectively; far-red emission occurs upon binding to Aβ,

Formal name: 2-[[5′-(4-hydroxyphenyl)[2,2′-bithiophen]-5-yl]-methylene]-propanedinitrile

Synonyms: 

Molecular weight: 334.4

CAS: 868592-56-7

Purity: ≥98%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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