An imidazole that has potent antibacterial properties in drug-resistant bacteria; in bacteria

NH125 – 50 mg

Brand:
Cayman
CAS:
278603-08-0
Storage:
-20
UN-No:
Non-Hazardous - /

NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria.{16459} In bacteria, NH125 inhibits several histidine kinases, inhibiting YycG with an IC50 of 6.6 µM.{16460} NH125 also decreases the viability of several cancer cell lines with IC50 values ranging from 0.7-4.7 µM.{16458} In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50 = 7.5 µM), protein kinase A (IC50 = 80 µM), and calmodulin-dependent kinase II (IC50 = 100 µM).{16458}  

 

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SKU: 10011250 - 50 mg Category:

Description

An imidazole that has potent antibacterial properties in drug-resistant bacteria; in bacteria, inhibits several histidine kinases, inhibiting YycG with IC50 values ranging from 0.7-4.7 µM; decreases viability of several cancer cell lines with IC50 values ranging from 0.7-4.7 µM

Formal name: 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide

Synonyms: 

Molecular weight: 524.6

CAS: 278603-08-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Kinase Inhibitors||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Death||Research Area|Cancer|Cell Signaling|CaMK Signaling||Research Area|Cancer|Cell Signaling|cAMP Signaling||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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