A fungal metabolite; inhibits the growth of the plant pathogenic fungi B. cinerea

NG 012 – 500 µg

Brand:
Cayman
CAS:
141731-76-2
Storage:
-20
UN-No:
Non-Hazardous - /

NG 012 is a fungal metabolite originally isolated from P. verruculosum that has fungicidal and nerve growth factor-potentiating properties.{45185,45186} It inhibits the growth of the plant pathogenic fungi B. cinerea, P. teres, P. lingam, S. sclerotiorum, and M. fructigena in vitro.{45185} NG 012 (50 μM) increases the efficacy of the antifungal miconazole (Item No. 15420) against C. albicans, reducing the IC50 value from 19.2 to 2.5 μM.{45187} It also potentiates neurite outgrowth induced by nerve growth factor (NGF) in PC12 cells in a concentration-dependent manner.{45186}  

 

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SKU: 27509 - 500 µg Category:

Description

A fungal metabolite; inhibits the growth of the plant pathogenic fungi B. cinerea, P. teres, P. lingam, S. sclerotiorum, and M. fructigena in vitro; increases the efficacy of miconazole against C. albicans, reducing the IC50 value from 19.2 to 2.5 μM when used at 50 μM; potentiates NGF-induced neurite outgrowth in PC12 cells in a concentration-dependent manner

Formal name: 7R,8,11S,12,15R,16,23R,24,27R,28-decahydro-2,4,18,20-tetrahydroxy-11-(hydroxymethyl)-7,15,23,27-tetramethyl-5H,9H,13H,21H,25H-dibenzo[k,u][1,5,9,15,19]pentaoxacyclotetracosin-5,9,13,21,25-pentone

Synonyms:  BK223-A

Molecular weight: 662.6

CAS: 141731-76-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Pesticides|Fungicides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Candidiasis||Research Area|Neuroscience||Research Area|Toxicology|Environmental

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