A fluorogenic substrate of MMPs; hydrolyzed rapidly by MMP-3 (kcat/Km = 218

NFF-3 – 5 mg

Brand:
Cayman
CAS:
158584-09-9
Storage:
-20
UN-No:
Non-Hazardous - /

NFF-3 is a fluorogenic substrate of matrix metalloproteinases (MMPs).{37000} NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1*M-1) and slowly by MMP-9 (kcat/Km = 10,100 s-1*M-1) with no significant hydrolysis by MMP-1 or MMP-2.{37000} NFF-3 can be used to differentiate MMP-3 activity from that of other MMPs.{37000, 37001}   

 

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Description

A fluorogenic substrate of MMPs; hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1*M-1) and slowly by MMP-9 (kcat/Km = 10,100 s-1*M-1); not hydrolyzed by MMP-1 or MMP-2; used to differentiate MMP-3 activity from that of other MMPs

Formal name: N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-valyl-L-α-glutamyl-L-norvalyl-L-tryptophyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysinamide

Synonyms: 

Molecular weight: 1,675.80

CAS: 158584-09-9

Purity: ≥95%

Formulation: A crystalline solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area

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