A synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling

NF-κB Inhibitor – 5 mg

Brand:
Cayman
CAS:
213546-53-3
Storage:
-20
UN-No:
Non-Hazardous - /

NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.{17866} It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.{17866} In this way, NF-κB inhibitor blocks gene expression that is regulated by NF-κB.{28516,28514} This peptide is commonly used to evaluate the role of NF-κB signaling in cellular responses.{28518,28517}  

 

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Description

A synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α

Formal name:

Synonyms:  SN50 Peptide

Molecular weight: 2,781.50

CAS: 213546-53-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Immunology & Inflammation|Innate Immunity|Pattern Recognition||Research Area|Immunology & Inflammation|Innate Immunity|STING||Research Area|Infectious Disease

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