A peptide that is identical in sequence to NF-κB inhibitor

NF-κB Control – 5 mg

Brand:
Cayman
CAS:
201608-17-5
Storage:
-20
UN-No:
Non-Hazardous - /

NF-κB inhibitor (Item No. 17493) is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.{17866} It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.{17866} NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids.{17866} It is ineffective at blocking the activation of NF-κB signaling and is used as a negative control peptide.{17866,28515,28513}  

 

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Description

A peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids; used as a negative control peptide

Formal name:

Synonyms:  SN50M

Molecular weight: 2,668.30

CAS: 201608-17-5

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Immunology & Inflammation|Innate Immunity|Pattern Recognition||Research Area|Immunology & Inflammation|Innate Immunity|STING||Research Area|Infectious Disease

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