A natural sapogenin that acts as a bioavailable

Neoruscogenin – 5 mg

Brand:
Cayman
CAS:
17676-33-4
Storage:
-20
UN-No:
Non-Hazardous - /

Neoruscogenin is a natural sapogenin isolated from Butcher’s broom (R. rhizoma), which is traditionally used against chronic venous disorders.{26498} It is a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (EC50 = 110 nM).{26497} In mice, neoruscogenin up-regulates the expression of several RORα-inducible genes in the liver, when given at 3 mg/kg/d orally for seven days.{26497}  

 

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Description

A natural sapogenin that acts as a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (EC50 = 110 nM); up-regulates the expression of several RORα-inducible genes in the livers of mice, when given at 3 mg/kg/d orally for seven days

Formal name: spirosta-5,25(27)-diene-1β,3β-diol

Synonyms:  25(27)-Dehydroruscogenin

Molecular weight: 428.6

CAS: 17676-33-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Saponins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area

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