An aminoglycoside antibiotic that inhibits protein translation by binding to the small subunit of prokaryotic ribosomes; commonly used for the prevention of bacterial contamination of cell cultures

Neomycin (sulfate) – 500 g

Brand:
Cayman
CAS:
1405-10-3
Storage:
22
UN-No:
Non-Hazardous - /

Neomycin is an aminoglycoside antibiotic produced by S. fradiae that inhibits protein translation by binding to the small subunit of prokaryotic ribosomes.{22680} It blocks voltage-sensitive Ca2+ channels and is a potent inhibitor of skeletal muscle sarcoplasmic reticulum Ca2+ release.{22682} Neomycin has been shown to inhibit inositol phospholipid turnover, phospholipase C, and phosphatidylcholine-phospholipase D activity (IC50 = 65 µM).{22681} It is highly effective against Gram-positive and Gram-negative bacteria and is commonly used for the prevention of bacterial contamination of cell cultures.  

 

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Description

An aminoglycoside antibiotic that inhibits protein translation by binding to the small subunit of prokaryotic ribosomes; commonly used for the prevention of bacterial contamination of cell cultures

Formal name: neomycin, trisulfate salt

Synonyms: 

Molecular weight: 908.9

CAS: 1405-10-3

Purity: ≥90%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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