Neohesperidin – 500 mg

Brand:
Cayman
CAS:
13241-33-3
Storage:
-20
UN-No:
Non-Hazardous - /

Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities.{39203,39204,39205} In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL).{39203} In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity.{39204} In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo.{39205}  

 

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SKU: 23028 - 500 mg Category:

Description

A flavonoid with diverse biological activities; inhibits osteoclast differentiation, bone resorption, activation of NF-κB and NFAT by RANKL, and calcium oscillations in vitro; in vivo administration protects ovariectomized mice from bone loss; reduces lipid accumulation in HepG2 cells and reverses hyperlipidemia in a mouse model of diet-induced obesity; increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in a mouse model of diabetes,


Formal name: (2S)-7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Synonyms:  Hesperetin 7-Neohesperidoside|NSC 31048

Molecular weight: 610.6

CAS: 13241-33-3

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Natural Products|Flavonoids||Research Area|Cardiovascular System|Lipids & Lipoproteins||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity